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Dr. Sean Conlan is an associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.​
… around the globe. CRE are resistant to most, if not all, antibiotics, with investigations reporting as high as a 40% … common feature of CRE is that genes encoding resistance to antibiotics are carried on mobile DNA sequences called … microbial genomics, human microbiome, DNA sequencing, antibiotics … Dr. Sean Conlan is an associate investigator in …
15 Ways Genomics Influences Our World
Genomics is advancing the study of individual and communities of microbes.
… You may have also heard of situations where the overuse of antibiotics in both the medical and agricultural fields has contributed to bacteria becoming resistant to antibiotics , because with more exposure, bacteria that … findings should make people think about the overuse  of antibiotics in our world, since in the most extreme cases of …
News Release
NHGRI participated in a science communications contest called the Three-Minute Talk. NHGRI's Ryan Johnson came away with a first place win.
… the KPC gene normally confers resistance to carbapenem antibiotics. Interestingly, we find that numerous …
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
… pressures on the skin biota, such as increased usage of antibiotics, less exposure to environmental microbes in soil …
Genetic Disorders
Severe Combined Immunodeficiency is a severe, genetic condition of the immune system.
… People afflicted with this disease often have to take antibiotics and supplemental infusions of antibodies to …
Genetic Disorders
Methylmalonic acidemia is a group of inherited disorders in which the body is unable to process certain proteins and fats (lipids) properly.
… a low-protein, high-calorie diet, certain medications, antibiotics and in some cases, organ transplantation. … (vitamin B12) given as an injection, carnitine, and antibiotics. The diet is protein restricted to limit the …
Staff
Dr. Julie Segre is chief and a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
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… virulent and has now evolved resistance to all known antibiotics. For the first time, MGS's real-time genomic …
News Release
On its 15th anniversary, National DNA Day and NHGRI shared its genomics expertise to explain the importance of genomics in our everyday lives.
… also the plague bacterium. Then bacteria resistant to antibiotics. Among these beasts you have some of the horseman … up--by failing to vaccinate our children, by overusing antibiotics (and triggering resistance), or by taking clean …
Media Advisory
The NIH-funded Integrative Human Microbiome Project presented at the International Human Microbiome Congress.
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.