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News Release
A new phase of the IGNITE Network will conduct clinical trials of genomic medicine interventions.
… management of diseases such as high blood pressure, depression and chronic pain. The trials are part of the … benefits. The second trial will focus on pain and depression – two conditions where finding safe and effective … there are few clinically useful predictors for whether a depression treatment will be successful, patients often …
For Patients and Families
​Pharmacogenomics combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.​
… of using drugs to manage heart disease, cancer, asthma, depression and many other common diseases. One current use of … health disorders. For example, while some patients with depression respond to the first drug they are given, many do … each drug takes weeks to take its full effect, patients' depression may grow worse during the time spent searching for …
Genetic Disorders
Dercum disease is a rare condition that is characterized by multiple, painful fatty tumors that occur chiefly in post-menopausal, obese women of middle age.
… (4) mental disturbances, including emotional instability, depression, epilepsy, confusion and dementia. The pain can … disease is often associated with generalized weakness, depression, and irritability. The condition can also be …
Diversity Center
The University of Texas Rio Grande Valley (UTRGV) has established a Diversity Center for Genome Research that will build UTRGV’s genomics research capacity by 1) expanding genomic research capabilities and discoveries in two innovative research projects; and 2) enhancing the size and quality of the available genomics workforce.
…  Genomic Approaches to Pollutome Effects on Risk of Major Depression in Hispanic Pedigrees Lead: John Blangero, Ph.D. …
Research Funding
The IGNITE PTN supports a network of multi-site clinical groups involving diverse settings and populations to conduct two pragmatic clinical trials of genomic medicine interventions.
… care") for acute post-surgical pain, chronic pain, and depression via changes in patient-reported outcomes representing pain and depression control. … Both GUARDD-US and ADOPT-PGx protocol … Disease Disparities in the United States (GUARDD-US) … A Depression and Opioid Pragmatic Trial in Pharmacogenetics …
Genetic Disorders
Attention Deficit Hyperactivity Disorder (ADHD) is a neurological disorder that affects a person's ability to control their behavior and pay attention to tasks.
… behavioral disorders or disorders of mood such as depression or anxiety. Problems with planning, memory, …
Staff
Dr. Simona Volpi is a program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
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… the genetic and genomic research areas of schizophrenia, depression and sleep disorders. Dr. Volpi completed her …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… 2006. The initial studies include bipolar disorder, major depression, kidney disease in type 1 diabetes, attention …
News Release
Clinical applications of genomics in neurology and psychiatry will be the focus of the 2014 lecture series Genomics in Medicine at Suburban Hospital.
… from brain diseases - including bipolar disease, major depression, schizophrenia, obsessive-compulsive disorder, …
News Release
Ten investigators will receive exome sequencing data as part of their clinical research projects at the NIH Clinical Center.
… sequencing of 75 patients to study treatment-resistant depression.  Joel Moss, M.D., Ph.D., National Heart, Lung, …