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Gene regulation is the process of turning genes on and off.
… Gene Regulation … Gene regulation is the process of turning genes on and off. … Gene …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… in the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene … University of California, Los Angeles "Ribonomics" Of Gene Regulation To Predict Innate Immune Responses …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… awards emanate from the recently launched Genomics of Gene Regulation (GGR) program of the National Human Genome … disease." With these new grants, researchers will study gene networks and pathways in different systems in the body, …
Policy Issues
Most genetic tests today are not regulated, meaning that they go to market without any independent analysis to verify the claims of the seller.
… the test predicts the presence or absence of a particular gene or genetic change. Can the test consistently and … has proposed new policies to enhance analytical validity regulation and expand oversight of the clinical validity of … policy of "enforcement discretion" (see next section, "FDA Regulation", for an explanation of the term "enforcement …
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… Tumor Suppressor Gene … A tumor suppressor gene directs the production of a protein that is part of the … cell division. … BRCA1, BRCA2, Cancer, Oncogene, Cell, Gene, Mutation … A tumor suppressor gene encodes a protein …
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… called enhancers, which act like switches to control gene activities. Dr. O'Shea's team wondered if the … Content … NIH researchers reveal link between powerful gene regulatory elements and autoimmune diseases … NIH … to regulating the human immune system. ​ … Immune system regulation, genomic switches in blood cells, autoimmune …
Educational Resources
The gene is the basic physical unit of inheritance.
… Gene … The gene is the basic physical unit of inheritance. … Inheritance, Gene, Double Helix, DNA, DNA Sequence … The gene is considered the basic unit of inheritance. Genes are …
Educational Resources
A candidate gene is a gene whose chromosomal location is associated with a particular disease or other phenotype.
… Candidate Gene … A candidate gene is a gene whose chromosomal location is associated with a … Traits, Disease, Linkage Analysis … The term candidate gene refers to a gene that is believed to be related to a …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… and investigate the health consequences of their genes and gene variants. … Reversing a Long-Standing Paradigm To … them to recall genotyped people and examine the genes and gene variants' influence on their phenotypes, an individual's … traits or symptoms and then searching for genes or gene variants that cause or contribute to them. NIH will …
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… Gene Environment Interaction … Gene environment interaction is an influence on the … … Genes, Environmental Factors, Genetics, DNA … Gene–environment interaction refers to the interplay of genes … ultraviolet radiation from the sun and social context. … Gene environment interaction is an influence on the …