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Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… translational genomics. Developing applications of genome technologies for the oncology clinic is an important priority … C, Ruchirawat M, Wang XW, TIGER-LC Consortium. Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and … M.D., Ph.D. … Paul Meltzer, functional genomics, molecular profiling technologies, osteosarcoma profiling, melanoma …
Research at NHGRI
The Genetics and Molecular Biology Branch uses genomic technologies to study the human genome and other organisms and disease mechanisms.
… The Genetics and Molecular Biology Branch uses state-of-the-art genetic and genomic technologies to study the genomes of humans and other … groups … Overview … Our Research … Genetics and Molecular Biology Branch … The Genetics and Molecular Biology …
Partner with NHGRI
NHGRI's technologies, inventions and discoveries are available for licensing.
… Numerous National Human Genome Research Institute (NHGRI) technologies, inventions and biological materials are … human-derived cell lines. For a complete list of our technologies as well as a list of technologies available from all other NIH Institutes, search …
Educational Resources
Microarray technology is a general laboratory approach that involves binding an array of thousands to millions of known nucleic acid fragments to a solid surface, referred to as a “chip.”
Research Funding
MorPhiC aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene by using in-vitro multicellular systems.
… genomes UM1 HG012654 Mazhar Adli Northwestern University Molecular and cellular characterization of essential human … Vision, MorPhiC aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every … catalog. Systematically obtaining information about the molecular and cellular phenotypic effects of gene knockouts …
Research at NHGRI
The Technology Transfer Office is responsible for transferring NHGRI technologies to the private sector and exchanging research materials with outside groups.
… for the benefit of the public health. … NHGRI's patented technologies are available licensing, including tissue microarrays for rapid molecular profiling, mouse models of inherited disorders and a diverse …
Administrative
The Information Technology Branch provides leadership and service for information technology resources at NHGRI.
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
Profile
Carlos Ferreira, M.D., staff clinician in NHGRI's Metabolic Medicine Branch, knows the catalogue of rare skeletal disorders well. With hundreds of known rare bone disorders and more to be discovered, Dr. Ferreira breaks down the challenges of skeletal genomics.
… not having a Ph.D. and having to learn not only the basic technologies, but also some novel technologies that appear all the time. I eventually learned … genomics? Ferreira: I’m hoping to incorporate new genomic technologies and try new therapies for patients. There are …
Research Funding
The Genome Technology Program is refining current technologies to increase efficiency and decrease cost while maintaining or improving data quality.
… supports research to innovate and develop new methods, technologies and systems that enable rapid, low-cost … and achieving orders-of-magnitude improvements in genomic technologies are foundational efforts of the program. The refinement of current technologies to increase efficiency and decrease cost while …