NHGRI logo

Enabling Cancer Research Through TCGA

On November 27-28, 2012, The Cancer Genome Atlas (TCGA) held its second annual scientific symposium at The Crystal Gateway Marriott in Crystal City, Va. Through collaborative workshops, poster sessions and plenary presentations, TCGA investigators from around the world shared their novel biological discoveries, analytical methods and translational approaches using TCGA data.

By November 2012, TCGA will have released data for more than 6000 cases of human cancer, with each case having mRNA/miRNA expression, copy number, promoter methylation, and mutation analysis datasets accessible. New data types, including protein array data have also become available.

 

 

 

Tuesday, November 27, 2012

1 TCGA Status Report and Insights From Leadership

Video | Slides
Kenna Shaw, Ph.D.
The Cancer Genome Atlas Program
2 TCGA Status Report and Insights From Leadership

Video | Slides
Stephen Chanock, M.D.
National Cancer Institute
3 TCGA Status Report and Insights From Leadership

Video | Slides
Louis M. Staudt, M.D., Ph.D.
National Cancer Institute
4 TCGA Status Reports and Insight from Leadership Q&A

Video
Matthew Meyerson, M.D.
Dana-Farber Cancer Institute

Ilya Shmulevich, Ph.D.
Institute for Systems Biology
5 TCGA Clear Cell Renal Cell Carcinoma Project

Video | Slides 
Chad J. Creighton, Ph.D.
Baylor College of Medicine
6 Analysis of Somatic Mutations Across Many Tumor Types

Video | Slides 
Petar Stojanov
Dana-Farber Cancer Institute/Broad Institute
7 CRAVAT and muPIT: Web Services for High-Throughput Analysis of Sequence Variation in Cancer 

Video | Slides
Rachel Karchin, Ph.D., M.S.
Johns Hopkins University
8 High-Grade Serous Ovarian Adenocarcinoma Transcriptome Sequencing

Video | Slides 
Andrew J. Mungall, Ph.D.
British Columbia Cancer Agency
9 Adverse Outcomes in Clear Cell Renal Cell Carcinoma With Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2

Video | Slides
Ari Hakimi, M.D.
Memorial Sloan-Kettering Cancer Center
10 Individual Patient Cancer Profiles in The Cancer Genome Atlas

Video | Slides
Jianjiong Gao, Ph.D.
Memorial Sloan-Kettering Cancer Center
11 Comprehensive Genomic Characterization of Squamous Cell Carcinoma of the Head and Neck

Video | Slides
David Neil Hayes, M.D.
The University of North Carolina at Chapel Hill
12 Genomic Characterization of Cancer-Adjacent Tissue: Evidence of Field Effects and Expression Subtypes

Video | Slides
Melissa Troester, Ph.D., M.P.H.
The University of North Carolina at Chapel Hill
13 Genome-Wide Analysis of Expression Quantitative Trait Loci in Breast Cancer

Video | Slides
Nicholas W. Knoblauch
Harvard Medical School
14 Pathway and Network Analysis of Somatic Mutations Across Cancer Types in TCGA

Video | Slides
Ben Raphael, Ph.D.
Brown University
15 Detection, Diagnosis and Correction of Batch Effects in TCGA Data 

Video | Slides
Rehan Akbani, Ph.D.
The University of Texas MD Anderson Cancer Center
16 Papillary Thyroid Carcinoma Analysis

Video | Slides
Thomas Giordano, M.D., Ph.D.
University of Michigan Medical School

 

Wednesday, November 28, 2012

17 The Bladder Cancer Analysis Working Group (BLCA AWG): A Progress Report

Video | Slides
John N. Weinstein, M.D., Ph.D.
The University of Texas MD Anderson Cancer Center
18 Identification of Gene Fusions Using RNA Sequencing Data

Video | Slides
Siyuan Zheng, Ph.D.
The University of Texas MD Anderson Cancer Center
19 Comparative Mutational Analysis in Frozen and FFPE Tumor Samples

Video | Slides
Gaddy Getz Ph.D.
The University of Texas MD Anderson Cancer Center / Broad Institute
20 Structural Variant Detection in Colorectal Cancer

Video | Slides
Evert van den Broek, M.D., Ph.D.
VU University Medical Center Amsterdam
21 FGFR2 and FGFR3 Mutations in Lung Squamous Cell Carcinoma Are Sensitive to Inhibition by Targeted Therapies

Video | Slides
Rachel G. Liao
Harvard University
22 Analysis of 3,000 Cancer Exomes to Identify Novel Cancer Drivers and Therapeutic Opportunities

Video | Slides
Nickolay Khazanov, Ph.D.
Compendia Bioscience
23 Integrated Genomic Characterization of Endometrial Carcinoma

Video | Slides
Douglas A. Levine, M.D.
Memorial Sloan-Kettering Cancer Center
24 Assessing Tumor Heterogeneity and Tracking Clonal Evolution Using Whole Genome or Exome Sequencing

Video | Slides
Christopher A. Miller, Ph.D.
The Genome Institute at Washington University
25 TCGA Benchmark 4: Evaluating SV and SNV Calls Using Cell Line Genomes

Video | Slides
Adam Ewing, Ph.D.
University of California, Santa Cruz
26 The Molecular Diversity of Luminal A Breast Tumors

Video | Slides
Giovanni Ciriello, Ph.D.
Memorial Sloan-Kettering Cancer Center
27 The Somatic Genomic Landscape of Glioblastoma Multiforme

Video | Slides
Roel Verhaak, Ph.D.
The University of Texas MD Anderson Cancer Center
28 Network-Based Stratification of Tumor Mutations

Video | Slides
Matan Hofree, M.S.
University of California, San Diego
29 Comprehensive Analysis of Lung Adenocarcinoma

Video | Slides
Matthew Meyerson, M.D.
Dana-Farber Cancer Institute
30 Predicting Time to Ovarian Carcinoma Recurrence Using Protein Markers

Video | Slides
Ji-Yeon Yang, Ph.D.
The University of Texas MD Anderson Cancer Center
31 Polymerase Epsilon Mutations Accelerate Mutation Rates in Colorectal and Endometrial Cancer

Video | Slides
David A. Wheeler, Ph.D.
Baylor College of Medicine
32 Virus Analysis in Head and Neck and Bladder Cancers

Video | Slides
Michael Parfenov, M.D., Ph.D., M.S.
Harvard Medical School
33 GeneSpot: A Portal for Interactive Gene-Centric Exploration of The Cancer Genome Atlas

Video | Slides
Brady Bernard, Ph.D. and Hector Rovira
Institute for Systems Biology
34 Functional Characterization of KEAP1 TCGA Mutants in Squamous Cell Carcinoma

Video | Slides 
Bridgid E. Hast
The University of North Carolina at Chapel Hill
35 Remarks About the Success of the TCGA Program

Video
Harold Varmus, M.D.
National Cancer Institute
36 Keynote Talk

Video | Slides
William Sellers, M.D.
Novartis Institutes for BioMedical Research, Inc.
37 Closing Remarks

Video
Matthew Meyerson, M.D.
Dana-Farber Cancer Institute
38 TCGA 2012 Poster Session

Video

 

Last updated: May 27, 2014